Plague - Mar 28, 2023 · Septicemic plague (Black Death or black plague) symptoms and signs include fever, weakness, abdominal pain, chills, and shock. Tissue bleeding and death may cause the dying tissues to appear black. Pneumonic plague symptoms and signs include characteristic pneumonia symptoms like chest pain, shortness of breath, cough, fever, chills, nausea ...

 
Plague Inc: Evolved is a unique mix of high strategy and terrifyingly realistic simulation. Your pathogen has just infected 'Patient Zero' - now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself. Recent Reviews: Overwhelmingly Positive (361) . Name

Collection. by Mark Cartwright. published on 26 March 2020. Plagues have swept through humanity ever since communities have gathered together in concentrated groups. In this collection of resources, we look at just some of the pandemics that raged throughout Antiquity and the Middle Ages, from the plague that ripped through Athens in the 5th ...List of epidemics and pandemics. 17th-century German "plague panel" depicting the triumph of death. Panels of this kind were placed on the walls of houses to warn against the plague. A plague epidemic raged in Augsburg, Bavaria, between 1632 and 1635. This is a list of the largest known epidemics and pandemics caused by an infectious disease.Mar 28, 2023 · Septicemic plague (Black Death or black plague) symptoms and signs include fever, weakness, abdominal pain, chills, and shock. Tissue bleeding and death may cause the dying tissues to appear black. Pneumonic plague symptoms and signs include characteristic pneumonia symptoms like chest pain, shortness of breath, cough, fever, chills, nausea ... Background. There are three types of plague. Most of the sick in 1665-1666 had bubonic plague. This created swellings (buboes) in the lymph nodes found in the armpits, groin and neck. Plague sufferers experienced headaches, vomiting and fever. They had a 30% chance of dying within two weeks. Plague definition, an epidemic disease that causes high mortality; pestilence. See more. Pneumonic plague is the most serious form of the disease and the only form that can spread from person to person. As a result of a bioterrorist attack, sick people would likely be seen outside the areas where plague naturally occurs due to the potential for release in other areas and person-to-person spread between close contacts.Synonyms for PLAGUE: afflict, persecute, torture, besiege, curse, attack, beset, torment; Antonyms of PLAGUE: help, aid, assist, relieve, release, deliver, abet, comfort Aug 6, 2021 · Plague is a disease that affects humans and other mammals. It is caused by the bacterium, Yersinia pestis. Humans usually get plague after being bitten by a rodent flea that is carrying the plague bacterium or by handling an animal infected with plague. Plague is infamous for killing millions of people in Europe during the Middle Ages. Experts believe that the name “Black Plague” was a mistranslation of the Latin word “atra mors” which could mean either “terrible” or “black.”. It was originally estimated that on average, a third of the population of affected areas was wiped out by the plague over its most destructive decade between 1346 and 1353, but other ...Plague should be considered in any patient with clinical signs of plague and a recent history of residence in or travel to the western United States or other plague endemic areas. Bubonic plague is the most common primary manifestation, with a bubo usually occurring in the groin, axilla, or cervical nodes.Define plague. plague synonyms, plague pronunciation, plague translation, English dictionary definition of plague. ) n. 1. a. A highly infectious epidemic disease ...plague of [sth] n. figurative ( [sth] bad and persistent) serie, ondata nf. Anna has suffered a plague of misfortunes. Anna è stata vittima di una serie di disgrazie. plague [sb/sth] ⇒ vtr. figurative, often passive (afflict) (figurato) flagellare ⇒ vtr. That country has been plagued by misfortune.noun. an epidemic disease that causes high mortality; pestilence. an infectious, epidemic disease caused by a bacterium, Yersinia pestis, characterized by fever, chills, and prostration, transmitted to humans from rats by means of the bites of fleas.: Compare bubonic plague, pneumonic plague, septicemic plague.Plague is transmitted between animals and humans by the bite of infected fleas, direct contact with infected tissues, and inhalation of infected respiratory droplets. Plague can be a very severe disease in people, with a case-fatality ratio of 30% to 60% for the bubonic type, and is always fatal for the pneumonic kind when left untreated.Mar 26, 2020 · Collection. by Mark Cartwright. published on 26 March 2020. Plagues have swept through humanity ever since communities have gathered together in concentrated groups. In this collection of resources, we look at just some of the pandemics that raged throughout Antiquity and the Middle Ages, from the plague that ripped through Athens in the 5th ... Pneumonic plague is the most serious form of the disease and the only form that can spread from person to person. As a result of a bioterrorist attack, sick people would likely be seen outside the areas where plague naturally occurs due to the potential for release in other areas and person-to-person spread between close contacts.Before covid-19, this was the world’s most recent pandemic, infecting as much as 21 percent of the world’s population. Swine flu was a hodgepodge of several different flu strains that had ...PLAGUE. Plague is a disease of rodents and their fleas that can be transmitted to humans. Throughout history, plague, often referred to as the " Black Death ," has caused catastrophic pandemics resulting in deaths of tens of millions of persons. The disease is caused by a gram-negative bacterium, Yersinia pestis.Nov 27, 2018 · New plague vaccines are in development but are not expected to be commercially available in the immediate future. Page last reviewed: November 27, 2018 Content source: Centers for Disease Control and Prevention , National Center for Emerging and Zoonotic Infectious Diseases (NCEZID) , Division of Vector-Borne Diseases (DVBD) This plague struck the earth, mainly Europe and Asia, from around 1346 to 1353. The plague killed between 75 and 200 million people. The cause of the plague was a bacterium called Yersinia pestis ...plague n. (infestation of insects or rats) invasion nf. (de moustiques, sauterelles,...) nuée nf. The citizens of Hamlin called on the services of the Pied Piper because of a plague of rats. Les citoyens de la ville de Hamelin ont fait appel au service du joueur de flûte à cause d'une invasion de rats. plague n. FIG 1. Transmission, diagnosis, treatment, and prevention of plague. Plague is a zoonotic disease caused by Yersinia pestis, whose natural life cycle includes rodents and fleas. Plague can be transmitted to humans through the bite of an infected flea, close contact with animals suffering from plague, or respiratory droplets of an infected ...Sep 4, 2023 · Pneumonic plague affects the lungs and causes symptoms similar to those of severe pneumonia: fever, weakness, and shortness of breath. Fluid fills the lungs and can cause death if untreated. Other symptoms may include insomnia, stupor, a staggering gait, speech disorder, and loss of memory. Septicemic plague is an infection of the blood. Its ... Apr 7, 2020 · Experts believe that the name “Black Plague” was a mistranslation of the Latin word “atra mors” which could mean either “terrible” or “black.”. It was originally estimated that on average, a third of the population of affected areas was wiped out by the plague over its most destructive decade between 1346 and 1353, but other ... Jul 23, 2021 · The plague is treatable in humans and animals if caught and addressed early. CBSN Denver noted that last year, two people in Colorado were confirmed to have contracted the plague, and both survived. Apr 16, 2020 · The Black Death of 1347-1352 CE is the most infamous plague outbreak of the medieval world, unprecedented and unequaled until the 1918-1919 CE flu pandemic in the modern age. The cause of the plague was unknown and, in accordance with the general understanding of the Middle Ages, was attributed to supernatural forces and, primarily, the will or ... Septicemic plague (Black Death or black plague) symptoms and signs include fever, weakness, abdominal pain, chills, and shock. Tissue bleeding and death may cause the dying tissues to appear black. Pneumonic plague symptoms and signs include characteristic pneumonia symptoms like chest pain, shortness of breath, cough, fever, chills, nausea ...The terms the plague or just plague (without the or a) refer to an infectious disease caused by a bacterium spread from rats to humans by means of flea bites. This plague is what is meant by the Black Death , which was a form of bubonic plague that spread over Europe in the 1300s and killed about a quarter of the population.The plague is treatable in humans and animals if caught and addressed early. CBSN Denver noted that last year, two people in Colorado were confirmed to have contracted the plague, and both survived.Synonyms for PLAGUE: afflict, persecute, torture, besiege, curse, attack, beset, torment; Antonyms of PLAGUE: help, aid, assist, relieve, release, deliver, abet, comfort plague n. (infestation of insects or rats) invasion nf. (de moustiques, sauterelles,...) nuée nf. The citizens of Hamlin called on the services of the Pied Piper because of a plague of rats. Les citoyens de la ville de Hamelin ont fait appel au service du joueur de flûte à cause d'une invasion de rats. plague n. Synonyms for PLAGUE: afflict, persecute, torture, besiege, curse, attack, beset, torment; Antonyms of PLAGUE: help, aid, assist, relieve, release, deliver, abet, comfort Plague is an illness you get from Yersinia pestis bacterium. You usually get the most common form (bubonic plague) from flea bites, but you can get pneumonic plague from someone who’s infected. Plague caused deadly pandemics in the past and still exists in many countries today. You can survive plague if you’re treated with antibiotics quickly.Nov 26, 2019 · Plague is a plausible diagnosis for people who are sick and live in, or have recently traveled to, the western United States or any other plague-endemic area. The most common sign of bubonic plague is the rapid development of a swollen and painful lymph gland called a bubo. A known flea bite or the presence of a bubo may help a doctor to ... plague meaning: 1. to cause worry, pain, or difficulty to someone or something over a period of time: 2. to annoy…. Learn more. Find 86 ways to say PLAGUE, along with antonyms, related words, and example sentences at Thesaurus.com, the world's most trusted free thesaurus.Mar 28, 2023 · Septicemic plague (Black Death or black plague) symptoms and signs include fever, weakness, abdominal pain, chills, and shock. Tissue bleeding and death may cause the dying tissues to appear black. Pneumonic plague symptoms and signs include characteristic pneumonia symptoms like chest pain, shortness of breath, cough, fever, chills, nausea ... List of epidemics and pandemics. 17th-century German "plague panel" depicting the triumph of death. Panels of this kind were placed on the walls of houses to warn against the plague. A plague epidemic raged in Augsburg, Bavaria, between 1632 and 1635. This is a list of the largest known epidemics and pandemics caused by an infectious disease. The plague is a serious bacterial infection that can be deadly. Sometimes referred to as the “black plague,” the disease is caused by a bacterial strain called Yersinia pestis.This bacterium ...May 18, 2023 · Plague. Plague, caused by the bacterium Yersinia pestis, is a disease that affects humans and other mammals. People typically get infected after being bitten by a rodent flea that is carrying the bacterium or by handling a plague-infected animal. Although the disease killed millions in Europe during the Middle Ages, antibiotics effectively ... plague: [noun] a disastrous evil or affliction : calamity. a destructively numerous influx or multiplication of a noxious animal : infestation. The bubonic plague - named the Black Death by later historians - was caused by the yersinia pestis bacteria, which lived in rodent populations and was spread by fleas that had bitten infected animals. Once the plague transferred to animals that were in close contact with humans and to humans themselves, it began to spread along established ...The Plague Runeword is a Weapon Runeword in Diablo II: Resurrected Patch 2.7 & Ladder Season 4, introduced in the Patch 2.4 Ladder Season 1. In this guide, we will give you quick facts about Plague, strengths and weaknesses, best classes and specs, best Mercenary use, best socketed base items to use to create this Runeword, and hints for farming the necessary Runes.Bubonic plague: Humans can come into contact with plague when an infected flea bites a person or when materials that have plague bacteria enter through a break (a cut or sore) in a person's skin. This is the most common form of plague. Pneumonic plague: Humans can come into contact with plague when a person breathes in plague bacteria from the air.The Black Death was a bubonic plague pandemic, which reached England in June 1348. It was the first and most severe manifestation of the second pandemic, caused by Yersinia pestis bacteria. The term Black Death was not used until the late 17th century. Originating in Asia, it spread west along the trade routes across Europe and arrived on the ...Mar 28, 2023 · Septicemic plague (Black Death or black plague) symptoms and signs include fever, weakness, abdominal pain, chills, and shock. Tissue bleeding and death may cause the dying tissues to appear black. Pneumonic plague symptoms and signs include characteristic pneumonia symptoms like chest pain, shortness of breath, cough, fever, chills, nausea ... Bubonic plague is one of three types of plague caused by the bacterium Yersinia pestis. [1] One to seven days after exposure to the bacteria, flu-like symptoms develop. [1] These symptoms include fever, headaches, and vomiting, [1] as well as swollen and painful lymph nodes occurring in the area closest to where the bacteria entered the skin. [2]Find 86 ways to say PLAGUE, along with antonyms, related words, and example sentences at Thesaurus.com, the world's most trusted free thesaurus. The plague hits Marseille, Paris and Normandy, and then the strain splits, with one strain moving onto the now-Belgian city of Tournai to the east and the other passing through Calais. and Avignon ...Plague, infectious disease caused by Yersinia pestis, a bacterium transmitted from rodents to humans by the bite of infected fleas. Plague has caused some of the most-devastating epidemics in history. It was the disease behind the Black Death of the 14th century, when as much as one-third of Europe’s population died.Plague Inc. is a unique mix of high strategy and terrifyingly realistic simulation with over 700 million games played! Your pathogen has just infected 'Patient Zero'. Now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself. Brilliantly executed ... plague: [noun] a disastrous evil or affliction : calamity. a destructively numerous influx or multiplication of a noxious animal : infestation. Jul 23, 2021 · The plague is treatable in humans and animals if caught and addressed early. CBSN Denver noted that last year, two people in Colorado were confirmed to have contracted the plague, and both survived. Plague. Plague is an infectious disease of animals and humans caused by a bacterium named Yersinia pestis. People usually get plague from the bite of a rodent flea that is carrying plague bacteria or by handling an infected animal. Although plague is a rare disease, about half of US cases each year occur in New Mexico.Sep 7, 2023 · Blurbs expose this ecosystem for what it really is: a nepotism-filled system that everyone endures for a chance of “making it” in an impossible industry for most. To borrow a phrase from ... plague翻译:不斷困擾;折磨;使受煎熬, (尤指因不停提問而)使煩惱,打攪, 瘟疫。了解更多。Plague: Directed by Nick Kozakis, Kosta Ouzas. With Don Bridges, Cris Cochrane, Tegan Crowley, Liza Dennis. A small group of survivors in post-apocalyptic Australia seek shelter from an infection that has spread like a plague among the human populace.Sep 4, 2023 · Pneumonic plague affects the lungs and causes symptoms similar to those of severe pneumonia: fever, weakness, and shortness of breath. Fluid fills the lungs and can cause death if untreated. Other symptoms may include insomnia, stupor, a staggering gait, speech disorder, and loss of memory. Septicemic plague is an infection of the blood. Its ... plague meaning: 1. to cause worry, pain, or difficulty to someone or something over a period of time: 2. to annoy…. Learn more.Plague is an illness you get from Yersinia pestis bacterium. You usually get the most common form (bubonic plague) from flea bites, but you can get pneumonic plague from someone who’s infected. Plague caused deadly pandemics in the past and still exists in many countries today. You can survive plague if you’re treated with antibiotics quickly.The bubonic plague - named the Black Death by later historians - was caused by the yersinia pestis bacteria, which lived in rodent populations and was spread by fleas that had bitten infected animals. Once the plague transferred to animals that were in close contact with humans and to humans themselves, it began to spread along established ... plague n. (infestation of insects or rats) invasion nf. (de moustiques, sauterelles,...) nuée nf. The citizens of Hamlin called on the services of the Pied Piper because of a plague of rats. Les citoyens de la ville de Hamelin ont fait appel au service du joueur de flûte à cause d'une invasion de rats. plague n.Evidence suggests Washtenaw County’s criminal legal system is rife with disparities based on race, and those are among the 65 recommendations of a sprawling new report released on Aug. 31 that ...Plague Inc: Evolved is a unique mix of high strategy and terrifyingly realistic simulation. Your pathogen has just infected 'Patient Zero' - now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself. Recent Reviews: Overwhelmingly Positive (361) Mar 17, 2020 · The plague resurfaced roughly every 10 years from 1348 to 1665—40 outbreaks in just over 300 years. And with each new plague epidemic, 20 percent of the men, women and children living in the ... Septicemic plague can occur as the first symptom of plague or may develop from untreated bubonic plague. This form results from bites of infected fleas or from handling an infected animal. Pneumonic plague: The incubation period of pneumonic plague is usually just 1 to 3 days. Patients develop fever, headache, weakness, and a rapidly developing ...Find 86 ways to say PLAGUE, along with antonyms, related words, and example sentences at Thesaurus.com, the world's most trusted free thesaurus. Plague. Plague is an infectious disease of animals and humans caused by a bacterium named Yersinia pestis. People usually get plague from the bite of a rodent flea that is carrying plague bacteria or by handling an infected animal. Although plague is a rare disease, about half of US cases each year occur in New Mexico. Antibiotics are effective ... Find 86 ways to say PLAGUE, along with antonyms, related words, and example sentences at Thesaurus.com, the world's most trusted free thesaurus.In the 17th century, people believed these outfits could purify poisonous air. They were wrong. During the 17th-century European plague, physicians wore beaked masks, leather gloves, and long ...Jul 23, 2021 · The plague is treatable in humans and animals if caught and addressed early. CBSN Denver noted that last year, two people in Colorado were confirmed to have contracted the plague, and both survived. Background. There are three types of plague. Most of the sick in 1665-1666 had bubonic plague. This created swellings (buboes) in the lymph nodes found in the armpits, groin and neck. Plague sufferers experienced headaches, vomiting and fever. They had a 30% chance of dying within two weeks.Septicemic plague (Black Death or black plague) symptoms and signs include fever, weakness, abdominal pain, chills, and shock. Tissue bleeding and death may cause the dying tissues to appear black. Pneumonic plague symptoms and signs include characteristic pneumonia symptoms like chest pain, shortness of breath, cough, fever, chills, nausea ...plague n. (infestation of insects or rats) invasion nf. (de moustiques, sauterelles,...) nuée nf. The citizens of Hamlin called on the services of the Pied Piper because of a plague of rats. Les citoyens de la ville de Hamelin ont fait appel au service du joueur de flûte à cause d'une invasion de rats. plague n. Nov 22, 2022 · Explore the history of the European plague doctor, and find out where their iconic outfit of a beaked mask and robe came from.--The year is 1656. Your body i... Black Death, pandemic that ravaged Europe between 1347 and 1351, taking a proportionately greater toll of life than any other known epidemic or war up to that time. The Black Death is widely thought to have been the result of plague, caused by infection with the bacterium Yersinia pestis.plague of [sth] n. figurative ( [sth] bad and persistent) ~의 재앙 명. Anna has suffered a plague of misfortunes. 안나는 불운의 재앙을 겪었다. plague [sb/sth] ⇒ vtr. figurative, often passive (afflict) ~에 피해를 주다, ~을 괴롭히다. That country has been plagued by misfortune.Apr 16, 2020 · The plague hits Marseille, Paris and Normandy, and then the strain splits, with one strain moving onto the now-Belgian city of Tournai to the east and the other passing through Calais. and Avignon ... Define plague. plague synonyms, plague pronunciation, plague translation, English dictionary definition of plague. ) n. 1. a. A highly infectious epidemic disease ...The Black Death of 1347-1352 CE is the most infamous plague outbreak of the medieval world, unprecedented and unequaled until the 1918-1919 CE flu pandemic in the modern age. The cause of the plague was unknown and, in accordance with the general understanding of the Middle Ages, was attributed to supernatural forces and, primarily, the will or ...Over 80% of United States plague cases have been the bubonic form. In recent decades, an average of seven human plague cases have been reported each year (range: 1–17 cases per year). Plague has occurred in people of all ages (infants up to age 96), though 50% of cases occur in people ages 12–45. It occurs in both men and women, though ...Black Death. The Black Death (also known as the Pestilence, the Great Mortality or the Plague) [a] was a bubonic plague pandemic occurring in Western Eurasia and North Africa from 1346 to 1353. It is the most fatal pandemic recorded in human history, causing the deaths of 75–200 million people, [1] peaking in Europe from 1347 to 1351.PLAGUE. Plague is a disease of rodents and their fleas that can be transmitted to humans. Throughout history, plague, often referred to as the " Black Death ," has caused catastrophic pandemics resulting in deaths of tens of millions of persons. The disease is caused by a gram-negative bacterium, Yersinia pestis.Plague is an infectious disease caused by the bacterium Yersinia pestis. Symptoms include fever, weakness and headache. Usually this begins one to seven days after exposure. There are three forms of plague, each affecting a different part of the body and causing associated symptoms.

The bubonic plague - named the Black Death by later historians - was caused by the yersinia pestis bacteria, which lived in rodent populations and was spread by fleas that had bitten infected animals. Once the plague transferred to animals that were in close contact with humans and to humans themselves, it began to spread along established ... . Pltn rb1vq

plague

The Plague. The first outbreak of plague swept across England in 1348-49. It seems to have travelled across the south in bubonic form during the summer months of 1348, before mutating into the ...Wright — a staff writer at The New Yorker, where the article that “The Plague Year” is based on first appeared — has performed a virtuoso feat and given us a book of panoramic breadth. It ...Apr 16, 2020 · The Black Death of 1347-1352 CE is the most infamous plague outbreak of the medieval world, unprecedented and unequaled until the 1918-1919 CE flu pandemic in the modern age. The cause of the plague was unknown and, in accordance with the general understanding of the Middle Ages, was attributed to supernatural forces and, primarily, the will or ... Plague was present in at least one location in the Islamic world virtually every year between 1500 and 1850. [56] Plague repeatedly struck the cities of North Africa. Algiers lost 30,000–50,000 to it in 1620–1621, and again in 1654–1657, 1665, 1691, and 1740–1742. [57] Plague is an illness you get from Yersinia pestis bacterium. You usually get the most common form (bubonic plague) from flea bites, but you can get pneumonic plague from someone who’s infected. Plague caused deadly pandemics in the past and still exists in many countries today. You can survive plague if you’re treated with antibiotics quickly. Bubonic plague can advance and spread to the lungs, which is the more severe type of plague called Pneumonic plague. Pneumonic plague – or lung-based plague – is the most virulent form of plague. Incubation can be as short as 24 hours. Any person with pneumonic plague may transmit the disease via droplets to other humans.Since the Act was enacted in 1966, NHTSA has recalled more than 390 million cars, trucks, buses, recreational vehicles, motorcycles, and mopeds. From 2018 through 2022 there were about 32 million ...Bubonic plague can advance and spread to the lungs, which is the more severe type of plague called Pneumonic plague. Pneumonic plague – or lung-based plague – is the most virulent form of plague. Incubation can be as short as 24 hours. Any person with pneumonic plague may transmit the disease via droplets to other humans.The bubonic plague was the most commonly seen form during the Black Death, with a mortality rate of 30-75% and symptoms including fever of 38 - 41 °C (101-105 °F), headaches, painful aching joints, nausea and vomiting, and a general feeling of malaise. Of those who contracted the bubonic plague, 4 out of 5 died within eight days. Plague - Bubonic, Pneumonic, Septicaemic: Plague is an ancient disease that was described during Classical times as occurring in North Africa and the Middle East. It is sometimes presumed to be the disease behind several historic epidemics, such as the pestilence described as striking the Philistines in the biblical book of 1 Samuel.Feb 28, 2022 · Plague is caused by Yersinia pestis bacteria. It can be a life-threatening infection if not treated promptly. Plague has caused several major epidemics in Europe and Asia over the last 2,000 years. Plague has most famously been called "the Black Death" because it can cause skin sores that form black scabs. A plague epidemic in the 14th century ... Sep 24, 2020 · History of Plague Epidemics. The plague has afflicted humanity for thousands of years.1, 2, 3 Molecular studies identified the presence of the Y. pestis plague DNA genome in 2 Bronze Age skeletons dated at roughly 3800 years old. 9 In the biblical book 1 Samuel from approximately 1000 BCE, the Philistines experience an outbreak of tumors associated with rodents, which might have been bubonic ... Responding to a Plague Bioterrorism Event. Kettles, buckets, lanterns, and other equipment were used in catching rats during the Public Health Service campaign against the New Orleans plague epidemic of 1914-1920. (Library of Medicine) Page last reviewed: February 7, 2022. Content source: Centers for Disease Control and Prevention, National ...noun. an epidemic disease that causes high mortality; pestilence. an infectious, epidemic disease caused by a bacterium, Yersinia pestis, characterized by fever, chills, and prostration, transmitted to humans from rats by means of the bites of fleas.: Compare bubonic plague, pneumonic plague, septicemic plague.Synonyms for PLAGUE: afflict, persecute, torture, besiege, curse, attack, beset, torment; Antonyms of PLAGUE: help, aid, assist, relieve, release, deliver, abet, comfortPlague Inc. is a unique mix of high strategy and terrifyingly realistic simulation with over 700 million games played! Your pathogen has just infected 'Patient Zero'. Now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself..

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